Hif1a分子量
Web14 de jan. de 2024 · In this study, we explored the role of hypoxia and HIF-1 in the ILC3 responses. We demonstrate that hypoxia increased numbers, proliferation and activation of ILC3 through a HIF-1α-dependent ... WebCITED2(216-246):Hif1a(796-826L822A) (Homo sapiens), CBP (340-439) (Mus musculus) Wright Add to Cart Sign Up for Our Newsletter. Receive the latest news, hot plasmids, …
Hif1a分子量
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WebCatalog #. AM16708. Standard 5 nmol. Purification: HPLC In-Vivo Ready Standard. Size: 5 nmol 20 nmol 20 nmol 20 nmol 20 nmol 40 nmol 40 nmol 100 nmol 250 nmol 250 … WebAbout This Kit. The Human HIF1A ELISA quantitates Hu HIF1A in human serum, plasma, or cell culture lysates. The assay will exclusively recognize both natural and recombinant …
Web17 de ago. de 2024 · Both HIF-1α and HIF-2α are required for the clear cell phenotype. Transcriptomic and proteomic analyses reveal that HIF-1α regulates glycolysis while HIF-2α regulates genes associated with lipoprotein metabolism, ribosome biogenesis and E2F and MYC transcriptional activities. Web17 de ago. de 2024 · To investigate whether HIF1A loss correlates with altered inflammation, we first demonstrated that HIF1A loss tumours exhibit on average between 1.9- and 2.1-fold higher levels of mRNA of CD3D ...
Web1 de set. de 2024 · Rabbit HIF1α antibody (GTX127309, GeneTex), Phospho-Y754-PDGFRα (Ab5460, Abcam), Phospho-AKT (S473) and AKT, Phospho-ERK (T202/Y204) and ERK, Phospho-EGFR (Y1068) and EGFR, and PDGFRβ (28E1) all from Cell Signaling Technology; rabbit PDGFRα (C20, sc338), mouse monoclonal PDGFRα (C9, sc … Web17 de jan. de 2024 · Mice with B cell-specific deletion of Hif1a have reduced number of IL-10-producing B cells, which result in exacerbated collagen-induced arthritis and …
WebHIF-1α は，低酸素誘導因子 HIF-1 の α サブユニットである。 HIF-1 は低酸素 hypoxia への適応に必要な遺伝子の転写を促進する転写因子 transcription factor で，α サブユニッ …
Web26 de fev. de 2024 · The competence of tumor cells to endure oxygen depletion is largely due to accumulation of Hypoxia-inducible factor 1 (HIF-1), a transcription factor consisting of an O 2 -responsive HIF-1α subunit... getty abductionWeb15 de set. de 2024 · The sizes of HIF1A-AS1 mRNA and HIF1A-AS2 mRNA were 652 and 2,051 nt. As shown in Fig. 1B, HIF1A-AS1 was complementary upon 117 nt to the HIF-1α mRNA 5′UTR (HIF1A-AS1: 117 to 1, HIF-1α mRNA: 307 to 423), while HIF1A-AS2 was complementary upon 1,221 nt to HIF-1α mRNA 3′UTR (HIF1A-AS2: 2,051 to 831, HIF … christopher modelewski part rulesWebFigure 2. HIF1A protein in macrophages is elevated in hemophagocytic lymphohistiocytosis (HLH) mouse models. (A) Schematic diagram depicting lymphocytic choriomeningitis virus (LCMV)-infected Prf1 − / − HLH mouse model. Perforin-deficient (Prf1 − / −) mice were infected with or without LCMV-WE of 200 plaque-forming units (PFU) via intraperitoneal … christopher mobley texasWeb25 de mai. de 2024 · Therapeutic targeting of the androgen signaling pathway is a mainstay treatment for prostate cancer. Although initially effective, resistance to androgen targeted therapies develops followed by disease progression to castrate-resistant prostate cancer (CRPC). Hypoxia and HIF1a have been implicated in the development of resistance to … christopher mobley storeWeb31 de mai. de 2013 · 小 中 大. HIF-1α的预测分子量为93kD，在变性充分的情况下可以检测到93kD的HIF-1α条带，在很多情况下可以检测到分子量为120kD左右的HIF-1α条带，原因 … christopher modenWebHIF1A. Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the HIF1A gene. [5] [6] [7] The Nobel Prize in … christopher modelewskiWeb7 de jul. de 2024 · Asiatic acid (AA) could attenuate ischemia/reperfusion induced myocardial apoptosis through upregulating the Akt/GSK-3β/HIF-1α pathway. HIF-3α is a negative regulator of HIF-1α, whose mRNA is a potential target of miR-1290. AA could upregulate miR-1290 in non-small-cell lung cancer A549 cells. getty abstract title