WebDec 24, 2013 · Collagen is the major constituent of the extracellular matrix component in tumors and plays a crucial role in tumor development. The aim of this study was to determine the mRNA expression of type XXI, XXII, XXIII and XXIV α1 collagen (COL21A1, COL22A1, COL23A1 and COL24A1, respectively) in head and neck squamous cell … WebDec 31, 2016 · Type XXII collagen is a member of the fibril-associated collagen with interrupted triple helices collagen family. The N terminus has a von Willebrand factor A domain and a thrombospondin domain ...
MGI:1916950 - collagen, type XXII, alpha 1 - Mouse Genome …
WebMar 29, 2024 · It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. WebOne example hereof is type XXII collagen (COL22). In this study, we investigated the biomarker potential of COL22 by measuring this in serum. An ELISA, named PRO-C22, was developed and measured in two serum cohorts consisting of patients with various solid tumors (n = 220) and healthy subjects (n = 33) (Cohort 1), and patients with pancreatic ... kate dicamillo facts for kids
Frontiers Skeletal Muscle Extracellular Matrix – What …
WebCollagen XVII is a transmembrane protein, like collagen XIII, XXIII and XXV. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Webcollagen, type XXII, alpha 1 Synonyms 2310067L16Rik, C80743 Feature Type protein coding gene IDs MGI:1916950 NCBI Gene: 69700 Alliance gene page Transcription Start Sites 5 TSS Location & Maps more Sequence Map Chr15:71667644-71906076 bp, - strand From Ensembl annotation of GRCm39 Genetic Map Chromosome 15, 32.31 cM Strain … WebApr 19, 2024 · Type I collagen is found throughout the body except in cartilaginous tissues. It is found in skin, tendon, vascular, ligature, organs and is the main component of bone. … kate dicamillo newbery winning books